BDBM50126039 4-[1-Hydroxy-1-(3-methyl-3H-imidazol-4-yl)-3-(4-pentyl-phenyl)-prop-2-ynyl]-2-naphthalen-1-yl-benzonitrile::CHEMBL24048
SMILES CCCCCc1ccc(cc1)C#CC(O)(c1cncn1C)c1ccc(C#N)c(c1)-c1cccc2ccccc12
InChI Key InChIKey=RLZPEQLIWYHFHH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50126039
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 3.80nMAssay Description:Inhibition of farnesylation in NIH-3T3H-ras cell lineMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human FTase-catalyzed incorporation of [3H]-FPP into recombinant Ras CVIMMore data for this Ligand-Target Pair